Fluorescence-Based Phenotypic Selection Allows Forward Genetic Screens in Haploid Human Cells
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منابع مشابه
Fluorescence-Based Phenotypic Selection Allows Forward Genetic Screens in Haploid Human Cells
The isolation of haploid cell lines has recently allowed the power of forward genetic screens to be applied to mammalian cells. The interest in applying this powerful genetic approach to a mammalian system is only tempered by the limited utility of these screens, if confined to lethal phenotypes. Here we expand the scope of these approaches beyond live/dead screens and show that selection for a...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2012
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0039651